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Technically, yes. Towards the end of Halo: Combat Evolved's campaign, one of the missions is to retrieve a neural implant that was inside Captain Keyes head. Upon arrival to the bridge where Captain Keyes was supposed to be, Master Chief finds a huge, disfigured, focal point of The Flood which the body of Keyes is now part of. Master Chief does the only thing he could do; He jabs his hand into his former commanding officer's skull and grabs the neural implant.

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